Small Error Algorithms for Tropical Group Testing

被引:1
作者
Paligadu, Vivekanand [1 ]
Johnson, Oliver [1 ]
Aldridge, Matthew [2 ]
机构
[1] Univ Bristol, Sch Math, Bristol BS8 1UG, England
[2] Univ Leeds, Sch Math, Leeds LS2 9JT, England
关键词
Testing; Analytical models; COVID-19; Adaptation models; Numerical models; Delays; Standards; Group testing; polymerase chain reaction (PCR) testing; tropical arithmetic; BOUNDS;
D O I
10.1109/TIT.2024.3445271
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
We consider a version of the classical group testing problem motivated by PCR testing for COVID-19. In the so-called tropical group testing model, the outcome of a test is the lowest cycle threshold (Ct) level of the individuals pooled within it, rather than a simple binary indicator variable. We introduce the tropical counterparts of three classical non-adaptive algorithms (COMP, DD and SCOMP), and analyse their behaviour through both simulations and bounds on error probabilities. By comparing the results of the tropical and classical algorithms, we gain insight into the extra information provided by learning the outcomes (Ct levels) of the tests. We show that in a limiting regime the tropical COMP algorithm requires as many tests as its classical counterpart, but that for sufficiently dense problems tropical DD can recover more information with fewer tests, and can be viewed as essentially optimal in certain regimes.
引用
收藏
页码:7232 / 7250
页数:19
相关论文
共 22 条
  • [11] The detection of defective members of large populations
    Dorfman, R
    [J]. ANNALS OF MATHEMATICAL STATISTICS, 1943, 14 : 436 - 440
  • [12] Du D., 1993, COMBINATORIAL GROUP
  • [13] Erlich Y., 2015, bioRxiv
  • [14] Ghosh S, 2020, medRxiv, DOI [10.1101/2020.04.23.20077727, 10.1101/2020.04.23.20077727, DOI 10.1101/2020.04.23.20077727]
  • [15] A Compressed Sensing Approach to Pooled RT-PCR Testing for COVID-19 Detection
    Ghosh, Sabyasachi
    Agarwal, Rishi
    Rehan, Mohammad Ali
    Pathak, Shreya
    Agarwal, Pratyush
    Gupta, Yash
    Consul, Sarthak
    Gupta, Nimay
    Ritika
    Goenka, Ritesh
    Rajwade, Ajit
    Gopalkrishnan, Manoj
    [J]. IEEE OPEN JOURNAL OF SIGNAL PROCESSING, 2021, 2 (02): : 248 - 264
  • [16] TWO-STAGE ADAPTIVE POOLING WITH RT-QPCR FOR COVID-19 SCREENING
    Heidarzadeh, Anoosheh
    Narayanan, Krishna
    [J]. 2021 IEEE INTERNATIONAL CONFERENCE ON ACOUSTICS, SPEECH AND SIGNAL PROCESSING (ICASSP 2021), 2021, : 8148 - 8152
  • [17] Performance of Group Testing Algorithms With Near-Constant Tests Per Item
    Johnson, Oliver
    Aldridge, Matthew
    Scarlett, Jonathan
    [J]. IEEE TRANSACTIONS ON INFORMATION THEORY, 2019, 65 (02) : 707 - 723
  • [18] NONRANDOM BINARY SUPERIMPOSED CODES
    KAUTZ, WH
    SINGLETON, RC
    [J]. IEEE TRANSACTIONS ON INFORMATION THEORY, 1964, 10 (04) : 363 - &
  • [19] A Narrative Systematic Review of the Clinical Utility of Cycle Threshold Values in the Context of COVID-19
    Rao, Sonia N.
    Manissero, Davide
    Steele, Victoria R.
    Pareja, Josep
    [J]. INFECTIOUS DISEASES AND THERAPY, 2020, 9 (03) : 573 - 586
  • [20] Tropical Group Testing
    Wang, Hsin-Po
    Gabrys, Ryan
    Vardy, Alexander
    [J]. IEEE TRANSACTIONS ON INFORMATION THEORY, 2023, 69 (09) : 6098 - 6120