Enhanced non-enzymatic multicomponent detection via one-step hydrothermal synthesis of widely dispersed Zn-SnO2 nanoparticles on nitrogen-doped reduced graphene oxide

被引：0

作者：

Baraneedharan, P. ^{[1
]}

J Sephra, Percy ^{[2
]}

机构：

[1] Department Electronics and Communication Engineering, Saveetha Engineering College, Chennai

[2] Department of Electronics and Communication Engineering, B.S. Abdur Rahman Crescent Institute of Science and Technology, Chennai

来源：

Materials Research Innovations | 2025年 / 29卷 / 02期

关键词：

catalytic activity; cholesterol; dopamine; Doping; glucose; graphene; hydrothermal; nanostructure;

D O I：

10.1080/14328917.2024.2383810

中图分类号：

学科分类号：

摘要：

Herein, we report a new type of non-enzymatic nanostructured biosensor designed for the concurrent determination of dopamine, cholesterol, and glucose in human blood samples. The prepared biosensor using low-temperature one-pot hydrothermal processing is a Zn-doped SnO2-dispersed nitrogen-doped reduced graphene oxide (N-rGO)/Zn-SnO2 nanocomposite. This modified electrode allows direct electron transfer and thus offers electrochemical techniques to detect target molecules in analytes without the use of enzymes. The biosensor displayed good voltammetric responses within the human reference range: 20–70 nM for dopamine, 1–8 mM for cholesterol, and 1–10 mM for glucose. It also showed excellent reusability and can be restored by washing with ethanol. Due to the use of Zn-doped SnO2 nanoparticles for enhanced catalytic activity and N-rGO for high conductivity and active sites, sensitive and selective detection can be achieved. This hybrid composite demonstrates excellent catalytic activity, repeatability, stability, and clinical comparability for real-time measurement of dopamine, cholesterol, and glucose simultaneously. © 2024 Informa UK Limited, trading as Taylor & Francis Group.

引用

页码：99 / 107

页数：8

共 23 条

[11]

Darabi R., Karimi-Maleh H., Akin M., Et al., Simultaneous determination of ascorbic acid, dopamine, and uric acid with a highly selective and sensitive reduced graphene oxide/polypyrrole-platinum nanocomposite modified electrochemical sensor, Electrochim Acta, 457, (2023)

[12]

Haritha V.S., Kumar S.R.S., Rakhi R.B., Amperometric cholesterol biosensor based on cholesterol oxidase and Pt-Au/MWNTs modified glassy carbon electrode

[13]

Baraneedharan P., Imran Hussain S., Dinesh V.P., Et al., Lattice doped Zn–SnO2 nanospheres: a systematic exploration of dopant ion effects on structural, optical, and enhanced gas sensing properties, Appl Surf Sci, 357, pp. 1511-1521, (2015)

[14]

Du D., Li P., Ouyang J., Nitrogen-doped reduced graphene oxide prepared by simultaneous thermal reduction and nitrogen doping of graphene oxide in air and its application as an electrocatalyst, ACS Appl Mater Interface, 7, 48, pp. 26952-26958, (2015)

[15]

Li Z., Deng L., Kinloch I.A., Et al., Raman spectroscopy of carbon materials and their composites: graphene, nanotubes and fibres, Prog Mater Sci, 135, (2023)

[16]

Li Y., Chen K., Yu H., Et al., Nitrogen-doped carbondots@COFBTH-TT composite for high-performance lithium ions battery anode, Ionics, 30, 1, pp. 95-103, (2024)

[17]

Zeng G., Li W., Ci S., Et al., Highly dispersed NiO nanoparticles decorating graphene nanosheets for non-enzymatic glucose sensor and biofuel cell, Sci Rep, 6, 1, pp. 1-8, (2016)

[18]

Zhang Z., Liu X., Wu Y., Et al., Synthesis and characterization of spherical Li2Fe0.5V0.5SiO4/C composite for high-performance cathode material of lithium-ion secondary batteries, J Electrochem Soc, 162, 4, pp. A737-A742, (2015)

[19]

Ji X., Zhao X., Zhang Z., Et al., Scalable fabrication of graphene-assembled multifunctional electrode with efficient electrochemical detection of dopamine and glucose, Nano Res, 16, 5, pp. 6361-6368, (2023)

[20]

Das S., Saha B., Tiwari M., Et al., Diagnosis of cancer using carbon nanomaterial-based biosensors, Sens Diagn., (2023)

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