DNA integrated nanostructures for optical-based detection of foodborne contaminants

被引:12
作者
Dadmehr, Mehdi [1 ,2 ]
Sangachin, Elnaz Ahmadi [3 ]
Bazzi, Fatima [3 ]
Li, Jiuxing [4 ]
Hosseini, Morteza [3 ]
机构
[1] Payame Noor Univ, Dept Biol, Tehran, Iran
[2] Mashhad Univ Med Sci, Fac Med, Dept Med Biotechnol & Nanotechnol, Mashhad, Iran
[3] Univ Tehran, Fac New Sci & Technol, Dept Life Sci Engn, Nanobiosensors Lab, Tehran, Iran
[4] McMaster Univ, Dept Biochem & Biomed Sci, 1280 Main St West, Hamilton, ON L8S 4L8, Canada
关键词
Optical; Biosensors; Food contaminant; DNA nanostructures; Detection; FLUORESCENT SILVER NANOCLUSTERS; STRAND DISPLACEMENT REACTION; DSDNA-TEMPLATED FORMATION; G-QUADRUPLEX; MOLECULAR BEACON; SENSITIVE DETECTION; METHYLATED DNA; MELAMINE; DNAZYME; APTAMER;
D O I
10.1016/j.trac.2024.117836
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Development of food detection strategies provides chances for the determination of contaminants in foodstuffs. Optical detection approaches which are based on light generation brought several advantages compared other applied strategies with higher sensitivity, selectivity, and rapidness properties. Among different reports, DNAbased biosensing platforms have been applied dramatically due to their variability and flexibility nature of DNA shapes and structures. DNA structures have been applied in both label-free and labeled forms in optical biosensors. In the present review, some of the marked optical detection investigations in recent years are discussed for detection of foodborne contaminants with emphasis on DNA's role in their construction. First, applied DNA-integrated nanostructures in biosensors that impact the recent advancement are briefly described. Then, among the major classified food contaminants, the most important optical approaches based on DNA-integrated nanostructures have been presented for target analytes. Finally, the outlook and perspectives of optical biosensing approaches are considered.
引用
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页数:14
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