Assessing Changes in Motor Function and Mobility in Individuals with Parkinson's Disease After 12 Sessions of Patient-Specific Adaptive Dynamic Cycling

被引:0
作者
Kim, Younguk [1 ,2 ]
Smith, Brittany E. [1 ]
Shigo, Lara [1 ]
Shaikh, Aasef G. [3 ,4 ]
Loparo, Kenneth A. [5 ]
Ridgel, Angela L. [1 ]
机构
[1] Kent State Univ, Exercise Sci & Exercise Physiol Program, Kent, OH 44242 USA
[2] Univ Alabama Birmingham, Dept Phys Med & Rehabil, Birmingham, AL 35233 USA
[3] Case Western Reserve Univ, Dept Neurol, Cleveland, OH 44106 USA
[4] Louis Stokes Cleveland VA Med Ctr, Cleveland, OH 44106 USA
[5] Case Western Reserve Univ, Inst Smart, Secure & Connected Syst, Cleveland, OH 44106 USA
关键词
wearable technology; neurorehabilitation; motor control; movement disorders; SMART EXERCISE BIKE; REHABILITATION; BRADYKINESIA; RELIABILITY; LEVODOPA;
D O I
10.3390/s24227364
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Background and Purpose: This pilot randomized controlled trial evaluated the effects of 12 sessions of patient-specific adaptive dynamic cycling (PSADC) versus non-adaptive cycling (NA) on motor function and mobility in individuals with Parkinson's disease (PD), using inertial measurement unit (IMU) sensors for objective assessment. Methods: Twenty-three participants with PD (13 in the PSADC group and 10 in the NA group) completed the study over a 4-week period. Motor function was measured using the Kinesia (TM) sensors and the MDS-UPDRS Motor III, while mobility was assessed with the TUG test using OPAL IMU sensors. Results: The PSADC group showed significant improvements in MDS-UPDRS Motor III scores (t = 5.165, p < 0.001) and dopamine-sensitive symptoms (t = 4.629, p = 0.001), whereas the NA group did not improve. Both groups showed non-significant improvements in TUG time. IMU sensors provided continuous, quantitative, and unbiased measurements of motor function and mobility, offering a more precise and objective tracking of improvements over time. Conclusions: PSADC demonstrated enhanced treatment effects on PD motor function compared to NA while also reducing variability in individual responses. The integration of IMU sensors was essential for precise monitoring, supporting the potential of a data-driven, individualized exercise approach to optimize treatment outcomes for individuals with PD.
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页数:13
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