Visible light induced hydroxyfluoroalkylation of quinoxalin-2(1H)-ones with N-trifluoroethoxyphthalimide under catalyst-free conditions

被引：0
|
作者：
Liu, Liting [1 ]
Liu, Jing [2 ]
Li, Siqi [1 ]
Yang, Mengfei [1 ]
Zhao, Xia [3 ]
Lu, Kui [1 ,2 ]
机构：
[1] Tianjin Univ Sci & Technol, Coll Biotechnol, China Int Sci & Technol Cooperat Base Food Nutr Sa, Tianjin 300457, Peoples R China
[2] Tianjin Univ Sci & Technol, Coll Sci, Dept Chem, Tianjin 300457, Peoples R China
[3] Tianjin Normal Univ, Coll Chem, Tianjin Key Lab Struct & Performance Funct Mol, Tianjin 300387, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2025年 / 23卷 / 03期
基金：
中国国家自然科学基金;
关键词：
FLUORINE;
D O I：
10.1039/d4ob01616e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
For the first time, we achieved visible light-induced direct C3-hydroxyfluoroalkylation of quinoxalin-2(1H)-ones using N-trifluoroethoxyphthalimide as the trifluoroethanol radical precursor, without the need for a photocatalyst. The metal-free and catalyst-free nature of this method makes it an efficient and environmentally friendly approach for synthesizing C3-hydroxyfluoroalkylated quinoxalin-2(1H)-ones.
引用
收藏
页码：629 / 637
页数：9
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