Visible light induced hydroxyfluoroalkylation of quinoxalin-2(1H)-ones with N-trifluoroethoxyphthalimide under catalyst-free conditions

被引：0

作者：

Liu, Liting ^{[1
]}

Liu, Jing ^{[2
]}

Li, Siqi ^{[1
]}

Yang, Mengfei ^{[1
]}

Zhao, Xia ^{[3
]}

Lu, Kui ^{[1
,2
]}

机构：

[1] Tianjin Univ Sci & Technol, Coll Biotechnol, China Int Sci & Technol Cooperat Base Food Nutr Sa, Tianjin 300457, Peoples R China

[2] Tianjin Univ Sci & Technol, Coll Sci, Dept Chem, Tianjin 300457, Peoples R China

[3] Tianjin Normal Univ, Coll Chem, Tianjin Key Lab Struct & Performance Funct Mol, Tianjin 300387, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2025年 / 23卷 / 03期

基金：

中国国家自然科学基金;

关键词：

FLUORINE;

D O I：

10.1039/d4ob01616e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

For the first time, we achieved visible light-induced direct C3-hydroxyfluoroalkylation of quinoxalin-2(1H)-ones using N-trifluoroethoxyphthalimide as the trifluoroethanol radical precursor, without the need for a photocatalyst. The metal-free and catalyst-free nature of this method makes it an efficient and environmentally friendly approach for synthesizing C3-hydroxyfluoroalkylated quinoxalin-2(1H)-ones.

引用

页码：629 / 637

页数：9

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