Bone response to zirconia ceramic implants: an experimental study in rabbit

被引：0

作者：

Di Carlo, F. ^{[1
]}

Prosper, L. ^{[1
]}

Ripari, F. ^{[1
]}

Scarano, A. ^{[1
]}

机构：

[1] Univ of Chieti and Rome, Italy

来源：

Key Engineering Materials | 2001年 / 192-195卷

关键词：

Bone - Ceramic materials - Formaldehyde - Growth kinetics - Histology - Implants (surgical) - Microscopic examination - pH - Tissue - Zirconia;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Aim of the present study was analysis between the bone response to Zirconia ceramic by Norton Desmarquest (Evreux, France). 5 New Zealand white mature male rabbits were used for this study. The implants of Zirconia ceramic were inserted into the tibia, and each rabbit received 4 implants. The animals were killed after 4 and 8 weeks. A total of 20 implants were retrieved. Implants and surrounding tissues were immediately fixed in 4% para-formaldehyde and 0.1% glutaraldehyde in 0.15 M cacodylate buffer al 4 C and pH 7.4, to be processed for histology. The specimens were processed to obtain thin ground sections with the Precise 1 Automated System (Assing, Rome, Italy). The slides were observed in normal transmitted light under a Leitz Laborlux microscope (Leitz, Wetzlar, Germany). A great quantity of newly-formed bone was observed in close contact with Zirconia ceramic surfaces; in some areas, many osteoblasts were present directly on the zirconia ceramic. After 8 weeks mature bone with few marrow space was present. Small actively secreting osteoblasts were present in the most coronal and apical portions of the implant. No inflammatory cells were present. In conclusion this study showed that Zirconia ceramic implant is highly biocompatible and osteoconductive.

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页码：403 / 407