[3,3]-Sigmatropic Rearrangements in the Enantioselective Synthesis of (-)-Methylenolactocin

被引：0
作者：
Ariza, Xavier [1 ]
Fernández, Natalia [1 ]
Garcia, Jordi [1 ]
López, Marta [1 ]
Montserrat, Laia [1 ]
Ortiz, Jordi [1 ]
机构：
[1] Dept. de Quím. Orgàn., Div. III, Universitat de Barcelona, 08028, Barcelona
来源：
| 1600年 / Georg Thieme Verlag卷
关键词：
Asymmetric synthesis; Dihidroxylations; Diols; Rearrangement;
D O I：
10.1055/s-2003-44351
中图分类号：
学科分类号：
摘要：
A Pd(II)-catalyzed [3,3]-sigmatropic rearrangement is used to transfer chirality from an enantio-enriched alk-3-ene-1,2-diol to a C2- symmetrical alk-2-ene-1,4-diol which, in turn, can be converted into a precursor of (-)-methylenolactocin through an additional [3,3]-sigmatropic rearrangement (either Johnson orthoester or Ireland-Claisen rearrangement).
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页码：128 / 134
页数：6
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