Surface modification of vascular tissue for targeted delivery of endothelial cells and microspheres

被引：0
|
作者：
Deglau, Timothy E. [1 ]
Litwak, Kenneth [1 ]
Villanueva, Flordeliza S. [1 ]
Wagner, William R. [1 ]
机构：
[1] Univ of Pittsburgh, Pittsburgh, United States
来源：
Annals of Biomedical Engineering | 2000年 / 28卷 / SUPPL. 1期
关键词：
Biopolymers - Blood vessels - Catheters - Cells - Controlled drug delivery - Hemodynamics - Proteins - Tissue;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A technique was developed to modify vascular tissue with proteinreactive polyethylene glycol[PEG]-biotin for targeting of cells or microspheres using the biotin/avidin recognition system. The resultant technique can be used for cell therapy, drug delivery, or gene therapy to modified vasculature following a surgical or catheter-based procedure.
引用
收藏
相关论文
共 50 条
  • [31] Internalization of targeted microbubbles by endothelial cells and drug delivery by pores and tunnels
    Beekers, Ines
    Langeveld, Simone A. G.
    Meijlink, Bram
    van der Steen, Antonius F. W.
    de Jong, Nico
    Verweij, Martin D.
    Kooiman, Klazina
    JOURNAL OF CONTROLLED RELEASE, 2022, 347 : 460 - 475
  • [32] Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo
    Wilson, A
    Zhou, W
    Champion, HC
    Alber, S
    Tang, ZL
    Kennel, S
    Watkins, S
    Huang, L
    Pitt, B
    Li, S
    MOLECULAR THERAPY, 2005, 12 (03) : 510 - 518
  • [33] Photodynamic effect of vascular-targeted polyphenol nanoparticles on Endothelial cells
    Yang, Lihua
    Liu, Danni
    Liu, Lian
    Jiang, Xian
    PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2024, 47
  • [34] Targeted Delivery of Immunoliposomes Containing Vascular Endothelial Growth Factor to Post Myocardial Infarction Tissue Improves Cardiac Function and Microvascular Perfusion
    Rosano, Jenna M.
    Scott, Robert C.
    Ivanov, Zhanna
    Wang, Bin
    Chong, Parkson Lee-Gau
    Crabbe, Deborah L.
    Kiani, Mohammad F.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 53 (10) : A305 - A305
  • [35] Tissue kallikrein is synthesized and secreted by human vascular endothelial cells
    Yayama, K
    Kunimatsu, N
    Teranishi, Y
    Takano, M
    Okamoto, H
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2003, 1593 (2-3): : 231 - 238
  • [36] Design of nanoparticles for targeted drug delivery: Surface modification of zirconium phosphate with PEG
    Rosas, Alyssa S.
    Diaz, Agustin
    Mosby, Brian
    Clearfield, Abraham
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [37] Liposome Microencapsulation for the Surface Modification and Improved Entrapment of Cytochrome c for Targeted Delivery
    Kajimoto, Kazuaki
    Katsumi, Tatsuhito
    Nakamura, Takashi
    Kataoka, Masatoshi
    Harashima, Hideyoshi
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2018, 95 (01) : 101 - 109
  • [38] Functional modification of vascular endothelial cells by cytokines during septic shock
    Endo, S
    Inada, K
    Yamada, Y
    Takakuwa, T
    Nakae, H
    Kasai, T
    Koike, S
    Inoue, Y
    Niimi, M
    Wakabayashi, G
    Taniguchi, S
    RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY, 1996, 94 (01) : 23 - 38
  • [39] Targeted delivery of microRNA-126 to vascular endothelial cells via REDV peptide modified PEG-trimethyl chitosan
    Zhou, Fang
    Jia, Xiaoling
    Yang, Qingmao
    Yang, Yang
    Zhao, Yunhui
    Fan, Yubo
    Yuan, Xiaoyan
    BIOMATERIALS SCIENCE, 2016, 4 (05) : 849 - 856
  • [40] Modification of glucose for targeted cellular delivery
    Jacobs, Harvey
    Witczak, Zbigniew
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
12345