Quantitative continuous measurement of pO2 and pCO2 in artery and vein

被引:0
作者
Pinard, E. [1 ]
Seylaz, J. [1 ]
Mamo, H. [1 ]
机构
[1] Lab. Physiol. Pathol. Cerebro-Vasc., Hop. Lariboisiere, Paris, France
关键词
BIOLOGICAL MATERIALS - Blood - CARBON DIOXIDE - Pressure Measurement - MASS SPECTROMETERS - Applications - OXYGEN - Pressure Measurement - POLYETHYLENES - Applications;
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摘要
A technique using a quadrupole mass spectrometer has been developed for continuous measurement of partial pressures of physiological blood gases. The depletion phenomenon is eliminated with a new sampling cannula equipped with a polyethylene membrane for velocities greater than 1 cm per second. The importance of this development resides in the fact that this phenomenon, due to a sampling rate around the cannula in excess of the replacement by the medium of the molecules withdrawn, leads to an under-estimation of the real partial pressure which increases as the blood velocity falls. With the new cannula, accurate measurements can now be made in both arteries and veins; moreover, continuous observation of physiological phenomena can be carried out with a time constant of under 1 minute because of the thinness of the membrane.
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页码:59 / 64
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