Derivatives of octahydropyrrolo[4,3,2-m,n]-acridine. 5. Alkylation of 1-methyl and 1-aryl-4,4,8,8-tetramethyl-2,3,4,5,7,8,9,10-octahydropyrrolo[4,3,2-m,n]acridin- 10-ones

被引：0

作者：

Uldrikis, Ya. ^{[1
]}

Visenieks, É. ^{[1
]}

Duburs, G. ^{[1
]}

机构：

[1] Latvian Institute of Organic Synthesis, Riga LV-1006, Latvia

来源：

Chemistry of Heterocyclic Compounds | 1998年 / 34卷 / 06期

关键词：

Aromatic compounds - Hydrides - Nitrogen - Sodium compounds;

D O I：

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学科分类号：

摘要：

4,4,8,8-Tetramethyl-2,3,4,5,7,8,9,10-octahydropyrrolo[4,3,2-m,n]acridin- 10- ones were alkylated at the nitrogen atom of the pyrrole ring by successive treatment with sodium hydride and an alkyl halide. Treatment of the neutral molecule with methyl iodide gave alkylation at the nitrogen atom of the pyridine ring. Derivatives of pyrrolo[4,3,2-m,n]acridine with no substituent at position 2 readily lost a proton from the NH group of the pyrrole ring to give bipolar structures. ©1998 Plenum Publishing Corporation.

引用

页码：692 / 699