Structural analysis of inhibitor binding to HIV-1 protease: identification of a common binding motif

被引:0
|
作者
Covell, D. G.
Jernigan, R. L.
Wallqvist, A.
机构
来源
关键词
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Binding of protons and cyclic urea inhibitors HIV-1 protease
    Gilson, MK
    Antosiewicz, J
    Trylska, J
    Hodge, CN
    Klabe, R
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 214 : 189 - COMP
  • [32] Structural analysis of an HIV-1 protease I47A mutant resistant to the protease inhibitor lopinavir
    Kagan, RM
    Shenderovich, MD
    Heseltine, PNR
    Ramnarayan, K
    PROTEIN SCIENCE, 2005, 14 (07) : 1870 - 1878
  • [33] Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates.: A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor
    Dohnálek, J
    Hasek, J
    Dusková, J
    Petroková, H
    Hradilek, M
    Soucek, M
    Konvalinka, J
    Brynda, J
    Sedlácek, J
    Fábry, M
    JOURNAL OF MEDICINAL CHEMISTRY, 2002, 45 (07) : 1432 - 1438
  • [34] Allosteric Suppression of HIV-1 Reverse Transcriptase Structural Dynamics upon Inhibitor Binding
    Seckler, James M.
    Barkley, Mary D.
    Wintrode, Patrick L.
    BIOPHYSICAL JOURNAL, 2011, 100 (01) : 144 - 153
  • [35] Identification of a common sphingolipid-binding domain in Alzheimer, prion, and HIV-1 proteins
    Mahfoud, R
    Garmy, N
    Maresca, M
    Yahi, N
    Puigserver, A
    Fantini, J
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (13) : 11292 - 11296
  • [36] 3D-Shape Analysis of the HIV-1 Protease Ligand Binding Site
    Kumar, Sunil
    Garg, Rajni
    Alla, Srinivas R.
    Zhang, Xiaoyu
    Jalahalli, Vivek K.
    2008 IEEE SYMPOSIUM ON COMPUTATIONAL INTELLIGENCE IN BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 2008, : 170 - +
  • [37] Computational proteomics analysis of binding mechanisms and molecular signatures of the HIV-1 protease drugs
    Verkhivker, Gennady
    ARTIFICIAL INTELLIGENCE IN MEDICINE, 2009, 45 (2-3) : 197 - 206
  • [38] Identification of a nucleotide binding site in HIV-1 integrase
    Drake, R. R.
    Neamati, N.
    Hong, H.
    Pilon, A. A.
    Proceedings of the National Academy of Sciences of the United States of America, 95 (08):
  • [39] The discovery, characterization and crystallographically determined binding mode of an FMOC-containing inhibitor of HIV-1 protease
    Rutenber, EE
    DeVoss, JJ
    Hoffman, L
    Stroud, RM
    Lee, KH
    Alvarez, J
    McPhee, F
    Craik, C
    deMontellano, PRO
    BIOORGANIC & MEDICINAL CHEMISTRY, 1997, 5 (07) : 1311 - 1320
  • [40] Molecular mechanisms of resistance: Free energy calculations of mutation effects on inhibitor binding to HIV-1 protease
    Rick, SW
    Topol, IA
    Erickson, JW
    Burt, SK
    PROTEIN SCIENCE, 1998, 7 (08) : 1750 - 1756