Asymmetric synthesis of α-amino acids

According to the synthetic methodology, the asymmetric synthesis of α-amino acids was reviewed, including asymmetric hydrogenation of α,β-didehydroamino acids, electrophilic addition of glycine equivalent in the presence of cPTC, electrophilic addition of glycine equivalent covalent bonded with chiral auxiliary, elaboration of chiral α-amino acids and chiral Strecker reaction.