Studies on the Synthesis of 2-(2-Bromophenyl)oxazoline

被引：0

作者：

Liu, Chun ^{[1
]}

Jiang, Jing-Yang ^{[1
]}

Liu, Xiao-Hang ^{[1
]}

Jin, Zi-Lin ^{[1
]}

机构：

[1] State Key Lab. Fine Chem. Technol., Dalian University of Technology, Dalian, 116012, China

来源：

Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities | / 20卷 / 04期

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摘要：

The synthetic method for 2-(2-bromophenyl)oxazoline was modified. The condensation reaction of N-(β-hydroxyethyl)-o-bromobenzamide to corresponding oxaozoline is performed by using SOCl2, not NaH reagent, with a elevated yield of up to 84%. The experimental results show that the reaction temperature has a great influence on the oxazoline yield. The oxazoline yield drop obviously with the rising of the reaction temperature and at room temperature hardly any oxazoline product formed. Based on the results obtained, it is presumed that ehe oxazoline ring was formed via an imide tautermer intermediate.

引用

页码：571 / 572