Palladium-catalyzed aryl cyanations with [14C]KCN: Synthesis of 14C-labelled fadrozole, a potent aromatase inhibitor

被引：0

作者：

Allentoff, Alban J. ^{[1
,2
]}

Markus, Bohdan ^{[1
]}

Duelfer, Timothy ^{[1
]}

Wu, Amy ^{[1
]}

Jones, Lawrence ^{[1
]}

Ciszewska, Grazyna ^{[1
]}

Ray, Tapan ^{[1
]}

机构：

[1] Isotope Laboratory, Novartis Pharmaceutical Corporation, Department of Drug Metabolism and Pharmacokinetics, 59 Route 10, East Hanover, NJ 07936, United States

[2] Isotope Laboratory, Novartis Pharmaceutical Corporation, Department of Drug Metabolism, 59 Route 10, East Hanover, NJ 07936, United States

来源：

| 2000年 / John Wiley and Sons Ltd卷 / 43期

关键词：

Aromatase inhibitors - Aryl iodides - Cyanation - Cyanation reaction - Disproportionations - Fadrozole - Imidazol - Palladium-catalyzed - Synthesised - [14C]potassium cyanide;

D O I：

10.1002/1099-1344(20001015)43:113.0.CO;2-F

中图分类号：

学科分类号：

摘要：

引用