Specificity of the Hairpin Ribozyme: Sequence Requirements Surrounding the Cleavage Site

被引:0
作者
Perez-Ruiz, Mercedes [1 ]
Barroso-DelJesus, Alicia [1 ]
Berzal-Herranz, Alfredo [1 ]
机构
[1] Inst. Parasitol. y Biomedicina L., Consejo Sup. de Invest. Cie., Ventanilla 11, 18001 Granada, Spain
来源
Journal of Biological Chemistry | / 274卷 / 41期
关键词
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:29376 / 29380
相关论文
共 50 条
[31]   Synthesis of uridine analogues to probe the functional group requirements of the hairpin ribozyme [J].
Vyle, JS ;
Young, KJ ;
Jones, S ;
Grasby, JA .
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1996, 61 :S280-S282
[32]   Catalytic Importance of a Protonated Adenosine in the Hairpin Ribozyme Active Site [J].
Suydam, Ian T. ;
Levandoski, Stephen D. ;
Strobel, Scott A. .
BIOCHEMISTRY, 2010, 49 (17) :3723-3732
[33]   A unique mechanism for RNA catalysis: the role of metal cofactors in hairpin ribozyme cleavage [J].
Hampel, A ;
Cowan, JA .
CHEMISTRY & BIOLOGY, 1997, 4 (07) :513-517
[34]   The sCYMV1 hairpin ribozyme: targeting rules and cleavage of heterologous RNA [J].
Lian, Y ;
De Young, MB ;
Siwkowski, A ;
Hampel, A ;
Rappaport, J .
GENE THERAPY, 1999, 6 (06) :1114-1119
[35]   Chemical synthesis of an artificially branched hairpin ribozyme variant with RNA cleavage activity [J].
Ivanov, SA ;
Volkov, EM ;
Oretskaya, TS ;
Müller, S .
TETRAHEDRON, 2004, 60 (41) :9273-9281
[36]   Polyamine dependent RNA cleavage:: Investigations on the function of spermine in hairpin ribozyme catalysis [J].
Welz, R ;
Müller, S .
CHEMISTRY OF NUCLEIC ACID COMPONENTS, 2002, 5 :251-255
[37]   The sCYMV1 hairpin ribozyme: targeting rules and cleavage of heterologous RNA [J].
Y Lian ;
M B De Young ;
A Siwkowski ;
A Hampel ;
J Rappaport .
Gene Therapy, 1999, 6 :1114-1119
[38]   Sequence requirements of the GPI-cleavage/addition site in rat acetylcholinesterase. [J].
Bon, S ;
Coussen, F ;
Massoulie, J .
MOLECULAR BIOLOGY OF THE CELL, 1996, 7 :1573-1573
[39]   The relaxed requirements of the integron cleavage site allow predictable changes in integron target specificity [J].
Frumerie, Clara ;
Ducos-Galand, Magaly ;
Gopaul, Deshmukh N. ;
Mazel, Didier .
NUCLEIC ACIDS RESEARCH, 2010, 38 (02) :559-569
[40]   Guiding ribozyme cleavage through motif recognition: The mechanism of cleavage site selection by a group II intron ribozyme [J].
Su, LHJ ;
Qin, PZ ;
Michels, WJ ;
Pyle, AM .
JOURNAL OF MOLECULAR BIOLOGY, 2001, 306 (04) :655-668