Cadmium deposition in rat heart following cadmium chloride and/or 60Co radiation

被引：0

作者：

Morgan, R. ^{[1
]}

Kundomal, Y. ^{[1
]}

Hupp, E. ^{[1
]}

机构：

[1] Minot State Univ, Minot, United States

来源：

Journal of Environmental Science and Health - Part A Environmental Science and Engineering | 1994年 / 29卷 / 01期

关键词：

Cardiovascular system - Environmental impact - Health hazards - Living systems studies - Radiation effects - Tissue - Waste disposal;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Male Sprague-Dawley rats were separated into nine groups and injected with cadmium (Cd) intraperitoneally every three days for 29 days for a total of nine injections. Injection doses ranged from 0 to 2.5 mg Cd/kg-1 of body weight. Twenty-four hours following Cd injections, rats received an acute whole body 60Co gamma radiation dose of 0, 3.62, or 5.43 Gray (Gy) at a dose rate of 3.04 Gy/min. Rats were sacrificed on day 1, 7, or 21 post-irradiation. Co-insult groups which had been irradiated following Cd injections showed lower Cd concentrations in heart tissue than those groups which had been injected with Cd and sham-irradiated. Our data indicate that radiation contributed to clearance of Cd from the heart. The present study points to a need for researchers to continue to study links between the environment and disease.

引用

页码：51 / 61