Asymmetric synthesis of 3-aryl-substituted 2,3-dihydro-1H-isoindol-1-ones

被引：0
|
作者：
Enders, Dieter [1 ]
Braig, Volker [1 ]
Raabe, Gerhard [1 ]
机构：
[1] Institut für Organische Chemie, R.-Westfalische Techn. Hochschule, Professor-Pirlet-Straße 1, 52074 Aachen, Germany
来源：
Canadian Journal of Chemistry | 2001年 / 79卷 / 11期
关键词：
Substitution reactions;
D O I：
10.1139/v01-140
中图分类号：
O6 [化学]; TQ03 [化学反应过程]; TQ02 [化工过程（物理过程及物理化学过程）];
学科分类号：
0703 ; 081701 ; 081704 ;
摘要：
The first asymmetric synthesis of 3-aryl substituted 2,3-dihydro-1H-isoindol-1-ones via a tandem nucleophilic 1,2-addition ring closure procedure from SAMP and (or) RAMP hydrazones and subsequent oxidative cleavage of the auxiliary is reported.
引用
收藏
页码：1528 / 1535
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