Effect of potent and selective Inhibitors of the Grb2 SH2 domain on cell motility

被引：0
|
作者：
Dept. of Oncology, K-136-4-26, Novartis Pharma AG, CH-4002 Basel, Switzerland [1 ]
不详 [2 ]
机构：
来源：
J Biol Chem | / 33卷 / 23311-23315期
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
31
引用
收藏
相关论文
共 50 条
  • [41] Development of Grb2 SH2 Domain Signaling Antagonists: A Potential New Class of Antiproliferative Agents
    Terrence R. Burke
    International Journal of Peptide Research and Therapeutics, 2006, 12 : 33 - 48
  • [42] Biological effects of synthetic peptide inhibitors of Grb2 SH2 in human breast cancer cells
    Lung, F.-D.
    Chen, M.-K.
    Lee, C.-Y.
    Chen, C.-H.
    Chuang, P.-H.
    BIOPOLYMERS, 2007, 88 (04) : 620 - 620
  • [43] Cyclic peptidyl inhibitors of Grb2 and tensin SH2 domains identified from combinatorial libraries
    Zhang, Yaniyan
    Zhou, Shanggen
    Wavreille, Anne-Sophie
    DeWille, James
    Pei, Dehua
    JOURNAL OF COMBINATORIAL CHEMISTRY, 2008, 10 (02): : 247 - 255
  • [44] Identification of phosphopeptide ligands for the Src-homology 2 (SH2) domain of Grb2 by phage display
    Gram, H
    Schmitz, R
    Zuber, JF
    Baumann, G
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 246 (03): : 633 - 637
  • [45] Binding of flexible and constrained ligands to the Grb2 SH2 domain: structural effects of ligand preorganization
    Clements, John H.
    DeLorbe, John E.
    Benfield, Aaron P.
    Martin, Stephen F.
    ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2010, 66 : 1101 - 1115
  • [46] Recent advances in the design and synthesis of SH2 inhibitors of Src Grb2 and ZAP-70
    Vu, CB
    CURRENT MEDICINAL CHEMISTRY, 2000, 7 (10) : 1081 - 1100
  • [47] Development of Grb2 SH2 domain signaling antagonists: A potential new class of antiproliferative agents
    Burke, TR
    INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2006, 12 (01) : 33 - 48
  • [48] Structure-based design of a non-peptidic antagonist of the SH2 domain of Grb2
    Caravatti, G
    Rahuel, J
    Gay, B
    Furet, P
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (14) : 1973 - 1978
  • [49] Design and synthesis of beta-aminomethylene phosphotyrosyl mimetics and their use in the preparation of macrocyclic Grb2 SH2 domain binding inhibitors
    Kang, SU
    Worthy, KM
    Bindu, L
    Karki, RG
    Nicklaus, MC
    Fisher, RJ
    Burke, TR
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U2740 - U2740
  • [50] Rational design of small peptides inhibitors of Grb2 SH2 domain in Ras signaling pathway and their prodrug as antiproliferative agents.
    Vidal, M
    Liu, WQ
    Rogues, BP
    Garbay, C
    CLINICAL CANCER RESEARCH, 2000, 6 : 4495S - 4495S
12345