Comparison of microemulsion electrokinetic chromatography and solvent-modified micellar electrokinetic chromatography

被引：0
|
作者：
Hansen, Steen Honoré [1 ,3 ]
Gabel-Jensen, Charlotte [1 ]
Pedersen-Bjergaard, Stig [2 ]
机构：
[1] Department of Analytical and Pharmaceutical Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark
[2] School of Pharmacy, University of Oslo, Oslo, Norway
[3] Department of Analytical and Pharmaceutical Chemistry, Royal Danish School of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen, Denmark
来源：
| 2001年 / Wiley-VCH Verlag卷 / 24期
关键词：
Methanol - Microemulsions - Organic solvents - Separation - Surface active agents;
D O I：
10.1002/1615-9314(20010801)24:83.0.CO;2-U
中图分类号：
学科分类号：
摘要：
Microemulsion electrokinetic chromatography (MEEKC) was investigated with the goal of elucidating the influence exerted by the amount of lipophilic organic phase and the amount of co-surfactant on the migration of a number of neutral test solutes. Furthermore, MEEKC was compared to solvent-modified micellar electrokinetic chromatography (MEKC). The organic solvents methanol, ethanol, 1-propanol, 1-butanol, acetonitrile, tetrahydrofuran, and 2-ethoxyethanol serving as co-surfactants in MEEKC were used in similar concentrations in MEKC systems in order to compare the selectivity and separation efficiency of the two kinds of system. The solvent-modified MEKC technique proved to be very similar to MEEKC in performance with respect to both separation selectivity and efficiency of separation.
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