Limulus amebocyte lysate reactivity, complement activation and patients' symptoms. Comparison of dialyzer membranes

被引:0
作者
Moss, A.H. [1 ]
Hamrick III, R.M. [1 ]
Shen, S.-H. [1 ]
机构
[1] West Virginia University School of Medicine, Morgantown, WV 26506, United States
来源
ASAIO Transactions | 1989年 / 35卷 / 04期
关键词
Biological Materials--Blood - Membranes;
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摘要
This study was undertaken to clarify the role of Limulus amebocyte lysate reactive material (LAL-RM) in the activation of complement in patients during hemodialysis with cuprophan membranes. The authors measured LAL-RM and completement C3a levels predialysis and at 15 and 60 minutes of dialysis in 16 patients dialyzed for 8 weeks on cuprophan membranes and then for a succeeding 8 weeks on cellulose acetate membranes. The LAL-RM and C3a levels rose significantly in the 16 patients while on dialysis with cuprophan membranes, but there was no correlation between the LAL-RM and C3a levels.
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页码:812 / 815
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