Optimized Large Scale Synthesis of Phosphorothioate Oligonucleotides on PS-PEG Supports

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Institute of Organic Chemistry, University of Tübingen, Auf der Morgenstelle 18, 72076 Tübingen, Germany ^{[1
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Z. Naturforsch. Sect. B J. Chem. Sci. | / 1卷 / 110-116期

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[31] LARGE-SCALE SYNTHESIS OF TRIPLE-HELIX FORMING OLIGONUCLEOTIDES USING A CONTROLLED-PORE GLASS SUPPORT
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BIOTECHNIQUES, 1993, 15 (06) : 1004 - &
[32] Transition from milligram to metric ton quantities of antisense oligonucleotides: Large-scale synthesis and manufacturing methodologies.
Cole, DL
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[33] PREPARATION OF N-15 LABELED NUCLEOSIDES AND LARGE-SCALE SYNTHESIS OF LABELED OLIGONUCLEOTIDES WITH A NEW TYPE DNA-SYNTHESIZER
FERA, B
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[34] SYNTHESIS OF S-ALKYL ESTERS OF PROTECTED 2'-DEOXYRIBONUCLEOSIDE 3'-PHOSPHOROTHIOATES - BUILDING-BLOCKS FOR THE LARGE-SCALE SYNTHESIS OF PHOSPHOROTHIOATE ANALOGS OF OLIGODEOXYRIBONUCLEOTIDES BY THE PHOSPHOTRIESTER APPROACH IN SOLUTION
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REESE, CB
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[35] Deoxyribonucleoside 3′-O-(2-thio- and 2-oxo-"spiro"-4,4-pentamethylene-1,3,2-oxathiaphospholane)s:: Monomers for stereocontrolled synthesis of oligo(deoxyribonucleoside phosphorothioate)s and chimeric PS/PO oligonucleotides
Stec, WJ
Karwowski, B
Boczkowska, M
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Blaszczyk, J
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[36] Optimized preparation of deca(L-alanyl)-L-valinamide by 9-fluorenylmethyloxycarbonyl (Fmoc) solid-phase synthesis on polyethylene glycol-polystyrene (PEG-PS) graft supports, with 1,8-diazobicyclo[5.4.0]-undec-7-ene (DBU) deprotection
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[37] Deoxyribonucleoside 3 prime -O-(2-thio- and 2-oxo-`spiro'-4,4-pentamethylene-1,3,2-oxathiaphospholane)s: Monomers for stereocontrolled synthesis of oligo(deoxyribonucleoside phosphorothioate)s and chimeric PS/PO oligonucleotides
J Am Chem Soc, 29 (7156-7167):
[38] LARGE-SCALE SYNTHESIS OF P-BENZOQUINONE-2'-DEOXYCYTIDINE AND P-BENZOQUINONE-2'-DEOXYADENOSINE ADDUCTS AND THEIR SITE-SPECIFIC INCORPORATION INTO DNA OLIGONUCLEOTIDES
CHENNA, A
SINGER, B
CHEMICAL RESEARCH IN TOXICOLOGY, 1995, 8 (06) : 865 - 874
[39] Low-temperature large-scale hydrothermal synthesis of optically active PEG-20 0 capped single domain MnFe2O4 nanoparticles
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JOURNAL OF ALLOYS AND COMPOUNDS, 2022, 904
[40] PREPARATION OF TECHNICAL GRADE POLYETHYLENE-GLYCOL (PEG) (MR20,000)-N-6-(2-AMINOETHYL)-NADH BY A PROCEDURE ADAPTABLE TO LARGE-SCALE SYNTHESIS
BUCKMANN, AF
MORR, M
KULA, MR
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 1987, 9 (03) : 258 - 268

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