Self-consistent simulations of electroporation dynamics in biological cells subjected to ultrashort electrical pulses

被引：61
|
作者：
Joshi, R.P. [1 ,1 ]
Hu, Q. [1 ,1 ]
Aly, R. [1 ,1 ]
Schoenbach, K.H. [1 ,1 ]
Hjalmarson, H.P. [1 ,1 ]
机构：
[1] Dept. of Elec. and Comp. Eng., Old Dominion University, Norfolk, VA 23529-0246, United States
来源：
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics | 2001年 / 64卷 / 1 I期
关键词：
Bessel functions - Cell membranes - Cells - Computer simulation - Electrophysiology - Hydrophilicity - Hydrophobicity - Mathematical models - Porous materials - Surface tension;
D O I：
10.1103/PhysRevE.64.011913
中图分类号：
学科分类号：
摘要：
A self-consistent model analysis of electroporation in biological cells was carried out based on the coupled Laplace-Nernst-Planck-Smoluchowski equations. The physical processes of pore generation, drift, and diffusion in r space were all comprehensively included. A pore-radius-dependent energy barrier to ionic transport accounted for cellular variations. As a result, predictions and qualitative understanding of the cellular response to short, high electric field pulses were obtained.
引用
收藏
页码：1 / 011913
相关论文
共 50 条
  • [1] Self-consistent simulations of electroporation dynamics in biological cells subjected to ultrashort electrical pulses
    Joshi, RP
    Hu, Q
    Aly, R
    Schoenbach, KH
    Hjalmarson, HP
    PHYSICAL REVIEW E, 2001, 64 (01):
  • [2] Simulations of electroporation dynamics and shape deformations in biological cells subjected to high voltage pulses
    Joshi, RP
    Hu, Q
    Schoenbach, KH
    Beebe, SJ
    IEEE TRANSACTIONS ON PLASMA SCIENCE, 2002, 30 (04) : 1536 - 1546
  • [3] Electroporation dynamics in biological cells subjected to ultrafast electrical pulses: A numerical simulation study
    Joshi, RP
    Schoenbach, KH
    PHYSICAL REVIEW E, 2000, 62 (01): : 1025 - 1033
  • [4] Improved energy model for membrane electroporation in biological cells subjected to electrical pulses
    Joshi, RP
    Hu, Q
    Schoenbach, KH
    Hjalmarson, HP
    PHYSICAL REVIEW E, 2002, 65 (04):
  • [5] Ultrashort electrical pulses open a new gateway into biological cells
    Schoenbach, KH
    Joshi, RP
    Kolb, JF
    Chen, N
    Stacey, M
    Buescher, ES
    Beebe, SJ
    Blackmore, P
    Proceedings of the 26th International Power Modulator Symposium and 2004 High Voltage Workshop, Conference Record, 2004, : 205 - 209
  • [6] Ultrashort electrical pulses open a new gateway into biological cells
    Schoenbach, KH
    Joshi, RP
    Kolb, JF
    Chen, NY
    Stacey, M
    Blackmore, PF
    Buescher, ES
    Beebe, SJ
    PROCEEDINGS OF THE IEEE, 2004, 92 (07) : 1122 - 1137
  • [7] SELF-CONSISTENT KLYSTRON SIMULATIONS
    CARLSTEN, BE
    TALLERICO, PJ
    IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1985, 32 (05) : 2837 - 2839
  • [8] Self-consistent dynamics of electromagnetic pulses and wakefields in laser-plasma interactions
    Bonatto, A.
    Pakter, R.
    Rizzato, F. B.
    LASER AND PARTICLE BEAMS, 2011, 29 (04) : 399 - 406
  • [9] Biological Cell Electroporation Using Nanosecond Electrical Pulses
    Khan, Omniyah Gul M.
    El-Hag, Ayman H.
    JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS, 2011, 1 (03) : 278 - 283
  • [10] Charge distributions for molecular dynamics simulations from self-consistent polarization method
    Stachowicz-Kusnierz, Anna
    Korchowiec, Beata
    Korchowiec, Jacek
    JOURNAL OF COMPUTATIONAL CHEMISTRY, 2020, 41 (30) : 2591 - 2597
12345