Medical applications of fullerenes and metallofullerenes

被引：0
|
作者：
Wilson, Lon J. [1 ]
机构：
[1] Department of Chemistry, Rice University
来源：
Electrochemical Society Interface | / 8卷 / 04期
关键词：
Antioxidants - Contrast media - Halogenation - Hydrogenation - Hydrophobicity - Magnetic resonance imaging - Medical applications - Nuclear medicine - Organometallics - Radioactive tracers - Solubility;
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摘要：
Empty fullerenes and endohedral metallofullerenes bring to medicine novel, 3-dimensional carbon structures that can be made water soluble, non-toxic and tissue or mission selective. In particular, endohedral metallofullerenes provide a new class of compounds for delivery of metal ions such as lanthanides in activated form for nuclear medicine and non-activated form as contrast media. Forthcoming breakthroughs in the synthesis and manipulation of these compounds promise lower cost, more sophisticated analogs capable of challenging present market-place technologies.
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页码：24 / 28
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