TOXICITY STUDIES OF A POLYURETHANE RIGID FOAM.

Relative toxicity tests were performed on a polyurethane rigid foam containing a trimethylolpropane-based polyol and an organophosphate flame retardant, a type of combination reported to be unusually toxic. No unusual toxicity was observed with either gradual or rapid pyrolysis to 800 degree C in the absence of air flow. Convulsions and seizures similar to those previously reported were observed when the material was essentially flash pyrolyzed at 800 degree C in the presence of air flow, and the toxicity appeared unusual because of the dramatic effect rather than because of low sample weights required to produce death.