Transforming growth factor beta (TGF-β) in bone remodelling

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作者：
Division of Surgery, Indian Veterinary Research Institute, Izatnagar 243 122, India [1 ]
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来源：
Curr. Sci. | / 8卷 / 613-617期
关键词：
'current - Bone fracture - Bone metabolism - Bone remodelling - Cellular activities - Clinical application - Fracture repair - Source types - TGF-β - Transforming growth factors;
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摘要：
The current concepts of the role of transforming growth-factor beta (TGF-β) with regard to bone metabolism and fracture repair are reviewed. The sources, types, chemistry, cellular activity and the clinical applications of TGF-β have been discussed. In low concentrations, this growth factor has significant effects on bone remodelling. The use of TGF-β for practical therapeutic purpose remains an exciting challenge.
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