EVERTING (TOPOSCOPIC) CATHETER FOR BROAD CLINICAL APPLICATION.
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作者:
Shook, D.R.
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Natl Inst of Health, Bethesda, MD,, USA, Natl Inst of Health, Bethesda, MD, USANatl Inst of Health, Bethesda, MD,, USA, Natl Inst of Health, Bethesda, MD, USA
Shook, D.R.
[1
]
Doppman, J.L.
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Natl Inst of Health, Bethesda, MD,, USA, Natl Inst of Health, Bethesda, MD, USANatl Inst of Health, Bethesda, MD,, USA, Natl Inst of Health, Bethesda, MD, USA
Doppman, J.L.
[1
]
Cattau Jr., E.L.
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Natl Inst of Health, Bethesda, MD,, USA, Natl Inst of Health, Bethesda, MD, USANatl Inst of Health, Bethesda, MD,, USA, Natl Inst of Health, Bethesda, MD, USA
Cattau Jr., E.L.
[1
]
Goldstein, S.R.
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Natl Inst of Health, Bethesda, MD,, USA, Natl Inst of Health, Bethesda, MD, USANatl Inst of Health, Bethesda, MD,, USA, Natl Inst of Health, Bethesda, MD, USA
Goldstein, S.R.
[1
]
机构:
[1] Natl Inst of Health, Bethesda, MD,, USA, Natl Inst of Health, Bethesda, MD, USA
The advanced development of the clinical everting (toposcopic) catheter is described. A detailed discussion of the design and outline of the fabrication techniques are followed by a thorough performance evaluation and summary of the first two clinical applications. The everting element is a low-durometer thermoplastic polyurethane elastomer. Surface treatments include the bonding of a hydrophilic polymeric coating, optimized for lubricity, to the sliding internal surfaces of the catheter. Eversion pressures and infusion/aspiration flow rates have been measured under various conditions and the infusate-in-blood mixing potential investigated. A preliminary assessment is given of the clinical performance of the catheter in the vascular delivery of chemotherapy and standard endoscopic retrograde cholangiopancreatography.