Trace-element data (including the rare-earth elements) in the crustal sequence of the Neotethyan Neyriz ophiolite in southwest Iran indicate normal mid-ocean ridge basalt (N-MORB) or island-arc tholeiite chemistry for the Tang-e Hana basalt. The data suggest that the Tang-e Hana rhyodacite, basalt, plagiogranite, and gabbro derived from a low-K tholeiitic parent magma. Trace-element distributions in amphibolite clasts, in the sole detachment of the ophiolite south of Lake Neyriz, correlate well with distributions in basalt clasts in the mélange and in the Tang-e Hana basalt. These trace elements suggest that the amphibolite originated from metamorphism and deformation of a tholeiitic basalt protolith. New 40Ar/39Ar incremental heating plateau ages from two hornblende plagiogranite specimens, in the crustal sequence in Tang-e Hana, are 92.07 ± 1.69 and 93.19 ± 2.48 Ma. Isotopic data for five Tang-e Hana basalts yield ΕNd values of +7.8 and +7.9, and 87Sr/86Sr values of 0.70368 to 0.70476. The isotopic compositions, ophiolite tectonostratigraphy, and correlation of the 40Ar/39Ar cooling (plagiogranite) and deformation (amphibolite) ages suggest emplacement of the Neyriz ophiolite either into an accretionary prism, through offscraping and subduction erosion, and (or) formation in a supra-subduction zone environment, around 82-96 Ma. Progressive accretion probably led to the development of a fore-arc basin and deposition of Upper Cretaceous - Eocene fore-arc and arc-derived sediments on the ophiolite. © 2006 NRC Canada.