External Validation of Accelerometry-Based Mechanical Loading Prediction Equations

Accurately predicting physical activity-associated mechanical loading is crucial for developing and monitoring exercise interventions that improve bone health. While accelerometer-based prediction equations offer a promising solution, their external validity across different populations and activity contexts remains unclear. This study aimed to validate existing mechanical loading prediction equations by applying them to a sample and testing conditions distinct from the original validation studies. A convenience sample of 49 adults performed walking, running, and jumping activities on a force plate while wearing accelerometers at their hip, lower back, and ankle. Peak ground reaction force (pGRF) and peak loading rate (pLR) predictions were assessed for accuracy. Substantial variability in prediction accuracy was found, with pLR showing the highest errors. These findings highlight the need to improve prediction models to account for individual biomechanical differences, sensor placement, and high-impact activities. Such refinements are essential for ensuring the models' reliability in real-world applications, particularly in clinical and biomechanical research contexts, where accurate assessments of mechanical loading are critical for designing rehabilitation programs, injury prevention strategies, and optimizing bone health interventions.