The experimental data available in literature were employed to build the incremental ratio function for relative permeability of two-phase medium. The effects of frequency, amplitude and time of vibration on permeability were analyzed by using this function. The relevant approach was assumed to be valid to the whole stratum. The forward difference method was used to simulate the wave propagation in stratum. In the simplified 1-D model, axial symmetric 2-D model and spherically symmetric 3-D model, the wave propagation in the two-phase medium with weak-condensability liquid and the distribution of relative permeability in stratum were analyzed. The effective range of vibration is close to the well bore. The vibration with the frequency of 10Hz makes the permeability increase by two times at the well head. The propagation distance of a wave is longer under low frequency vibration.