Response of capillaries and small arterioles to full-field flicker is not dependent on local ganglion cell thickness

被引：0

作者：

Sobczak, Marcelina ^{[1
,2
]}

Walker, Brittany r. ^{[1
]}

Gast, Thomas ^{[1
]}

Cassavaugh, Nicholas ^{[1
]}

Carmichael-martins, Alessandra ^{[1
]}

Burns, Stephen a. ^{[1
]}

机构：

[1] Indiana Univ, Sch Optometry, Bloomington, IN 47405 USA

[2] Wroclaw Univ Sci & Technol, Dept Opt & Photon, Wroclaw, Poland

来源：

BIOMEDICAL OPTICS EXPRESS | 2025年 / 16卷 / 01期

基金：

美国国家卫生研究院;

关键词：

BLOOD-FLOW; OPTIC-NERVE; FUNCTIONAL HYPEREMIA; LUMINANCE; PERICYTES; DIAMETER; RETINA; BRAIN; INNER; DISC;

D O I：

10.1364/BOE.544772

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

To measure the influence of ganglion cell layer (GCL) thickness on the changes in size and red blood cell (RBC) flow in small retinal vessels evoked by full-field flicker. We used a dual-beam adaptive optics scanning laser ophthalmoscope to image 11 healthy young controls in two retinal areas with significantly different GCL thicknesses. All capillaries and arterioles of the superficial vascular plexus were responsive to the flicker stimulation. Average lumen dilation and RBC flow changes were greater in capillaries than in arterioles (vasodilation: 10.9%, 6.7%; RBC flow: 51%, 38%, respectively). No statistically significant differences regarding relative lumen diameter, RBC velocity, or RBC flow were found with respect to GCL thickness, or vessel size. (c) 2024 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement

引用

页码：42 / 56

页数：15

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