Preparation of collagen burn-healing membranes

Collagen protein is obtained from fresh pigskin through hydrolysis with trypsin. By further adding extracts from scutellaria baicalensis (a Chinese herb), glutaraldehyde and etc., a novel type of collagen burn-healing membrane can be prepared. This novel type of membrane has a porous cross-linked netlike structure. The degree of crosslinking and mechanical properties of the membrane are examined; the optimal formulation and process parameters within preparation of the membrane are summarized. Based on the results from an in vitro test, the membrane enables its embedded medicines to possess a long-acting and slow-releasing property. © 2014, Journal of Chemical and Pharmaceutical Research. All rights reserved.