Regiospecific chlorination of (S)-β-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027

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作者
Lin, Shuangjun [1 ]
Van Lanen, Steven G. [1 ]
Shen, Ben [1 ,2 ,3 ,4 ]
机构
[1] Division of Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, WI 53705, United States
[2] University of Wisconsin National Cooperative Drug Discovery Group, University of Wisconsin-Madison, Madison, WI 53705, United States
[3] Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53705, United States
[4] School of Pharmacy, University of Wisconsin-Madison, 777 Highland Ave., Madison, WI 53705, United States
来源
Journal of the American Chemical Society | 2007年 / 129卷 / 41期
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Journal article (JA)
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页码:12432 / 12438
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