Mechanisms of cardiac impulse propagation and arrhythmogenesis

被引:0
作者
Honjo, Haruo [1 ]
机构
[1] Department of Cardiovascular Research, Research Institute of Environmental Medicine, Nagoya University
来源
Transactions of Japanese Society for Medical and Biological Engineering | 2015年 / 53卷 / 03期
基金
日本学术振兴会;
关键词
Arrhythmia; Cardiac impulse propagation; Spiral wave;
D O I
10.11239/jsmbe.53.123
中图分类号
R318.08 [生物材料学]; Q [生物科学];
学科分类号
07 ; 0710 ; 0805 ; 080501 ; 080502 ; 09 ;
摘要
Cardiac impulse propagation is determined by complex interactions between electrical activity of myocardiocytes, intercellular electrical communication and the myocardial tissue structure. A special form of conduction that underlies cardiac arrhythmias, including tachycardia and fibrillation, involves circulating excitation, spiral wave reentry. In this type of impulse propagation, curvature of the propagating excitation wavefront plays additional important roles. This brief review describes results from mathematical simulations and animal experiments to define mechanisms of normal and abnormal impulse conduction in the heart. © 2015, Japan Soc. of Med. Electronics and Biol. Engineering. All rights reserved.
引用
收藏
页码:123 / 129
页数:6
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