Engineering bacterial processes for cellulosic ethanol production

被引:0
作者
Kambam P.K.R. [1 ]
Henson M.A. [1 ]
机构
[1] Department of Chemical Engineering, University of Massachusetts, Amherst
关键词
D O I
10.4155/bfs.10.46
中图分类号
学科分类号
摘要
Over the past decade, ethanol has emerged as the single most-important alternative fuel to gasoline. In many countries, a blend of gasoline and alcohol (gasohol) is being supplied as a liquid fuel for transportation. Bioethanol produced from agricultural feed stocks is renewable in nature and reduces the problem of ghg emissions associated with petroleum-derived gasoline. While most current processes for production of bioethanol are dependent on microbial fermentation of food feedstocks (e.g., corn and sugarcane), second-generation technology based on the fermentation of nonfood feedstocks (e.g., corn stover and switch grass) is under development. Successful commercialization of bioethanol production requires an efficient microbe, rapid hydrolysis of feedstock into fermentable sugars and an optimized fermentation process. This article consolidates the current state of the art in upstream processing of cellulose for bioethanol production with bacteria. Recent advances in microbial cocultures involving one or more bacteria for efficient production of bioethanol are also discussed. The importance of engineering bacterial processes for efficient cellulosic bioethanol production is emphasized. © 2010 Future Science Ltd.
引用
收藏
页码:729 / 743
页数:14
相关论文
共 154 条
[21]  
Chabannes M., Barakate A., Lapierre C., Et al., Strong decrease in lignin content without significant alteration of plant development is induced by simultaneous down-regulation of cinnamoyl coa reductase (CCR) and cinnamyl alcohol dehydrogenase (CAD) in tobacco plants, Plant J., 28, 3, pp. 257-270, (2001)
[22]  
Hu W.J., Harding S.A., Lung J., Et al., Repression of lignin biosynthesis promotes cellulose accumulation and growth in transgenic trees, Nat. Biotechnol, 17, 8, pp. 808-812, (1999)
[23]  
Li Y.C., Irwin D.C., Wilson D.B., Processivity, substrate binding, and mechanism of cellulose hydrolysis by Thermobifida fusca ce19a, Appl. Environ. Microbiol, 73, 10, pp. 3165-3172, (2007)
[24]  
Pilate G., Guiney E., Holt K., Et al., Field and pulping performances of transgenic trees with altered lignification, Nat. Biotechnol, 20, 6, pp. 607-612, (2002)
[25]  
Ralph J., Akiyama T., Kim H., Et al., Effects of coumarate 3-hydroxylase down-regulation on lignin structure, J. Biol. Chem, 281, 13, pp. 8843-8853, (2006)
[26]  
Chapple C., Ladisch M., Meilan R., Loosening lignin's grip on biofuel production, Nat. Biotechnol, 25, 7, pp. 746-748, (2007)
[27]  
Chen F., Dixon R.A., Lignin modification improves fermentable sugar yields for biofuel production, Nat. Biotechnol, 25, 7, pp. 759-761, (2007)
[28]  
Boraston A.B., Bolam D.N., Gilbert H.J., Davies G.J., Carbohydrate-binding modules: Fine-tuning polysaccharide recognition, Biochem. J., 382, pp. 769-781, (2004)
[29]  
Mccartney L., Blake A.W., Flint J., Et al., Differential recognition of plant cell walls by microbial xylan-specific carbohydrate-binding modules, Proc. Natl. Acad. Sci. US.A., 103, 12, pp. 4765-4770, (2006)
[30]  
Obembe O.O., Jacobsen E., Timmers J., Et al., Promiscuous, non-catalytic, tandem carbohydrate-binding modules modulate the cell-wall structure and development of transgenic tobacco (Nicotiana tabacum) plants, J. Plant Res, 120, 5, pp. 605-617, (2007)