Transition-metal-free and solvent-tolerant decarboxylative iodination of aromatic carboxylic acids

被引：0

作者：

Wu, Cheng-Yan ^{[1
]}

Zhang, Xi ^{[2
]}

Zhang, Tian-Yi ^{[2
]}

Lu, Zhong-Lin ^{[2
]}

机构：

[1] Bohai Univ, Inst Ocean Res, Coll Chem & Mat Engn, Jinzhou, Peoples R China

[2] Beijing Normal Univ, Coll Chem, Beijing, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2025年 / 55卷 / 01期

关键词：

Aryl carboxylic acids; decarboxylative iodination; iodine monochloride; iododecarboxylation; DERIVATIVES; BROMODECARBOXYLATION; EFFICIENT; MECHANISM; ACETATE; ANALOGS;

D O I：

10.1080/00397911.2024.2428650

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Current decarboxylative halogenation methods typically require expensive or toxic transition metal catalysts and have limited solvent compatibility. Herein, we report a novel transition-metal-free and solvent-tolerant decarboxylative iodination method by using iodine monochloride in the presence of potassium phosphate, which are effective to readily available aryl and heteroaryl carboxylic acids, and can be executed in a variety of solvents, including water.

引用

页码：84 / 91

页数：8

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