Synthesis of aryl {4-[({5-[3-(methylsulfonyl)phenyl]pyrazin-2-yl}-oxy)methyl]piperidin-1-yl}methanones

被引：0

作者：

Sriramudu, B. ^{[1
]}

Satyanarayana, B. ^{[1
]}

Muralikrishna, P. ^{[1
]}

Ramachandran, D. ^{[1
]}

机构：

[1] Department of Chemistry, Acharya Nagarjuna University, Guntur,A.P, India

来源：

Journal of Chemical and Pharmaceutical Research | 2014年 / 6卷 / 07期

关键词：

Aromatic compounds;

D O I：

暂无

中图分类号：

O62 [有机化学]; TQ [化学工业];

学科分类号：

070303 ; 0817 ; 081704 ;

摘要：

Pyrazine nucleus potent biological activities with remarkable pharmaceutical importance and some of their derivatives occur as natural products. In view of these findings, it made interest to synthesize 2-(piperidin-4- ylmethoxy) pyrazines derivatives by the condensation of 2-[3-(methylsulfonyl) phenyl]-5-(piperidin-4-ylmethoxy) pyrazine with various aromatic acid chlorides in the presence of diisopropyl amine (DIPA). © 2014 Journal of Chemical and Pharmaceutical Research. All rights reserved.

引用

页码：1873 / 1883