Mimicking cellular environments by nanostructured soft interfaces

被引:108
作者
Department of New Materials and Biosystems, Max-Planck-Institute for Metals Research, University of Heidelberg, Heisenbergstrasse 3, D-70569 Stuttgart, Germany [1 ]
不详 [2 ]
不详 [3 ]
机构
[1] Department of New Materials and Biosystems, Max-Planck-Institute for Metals Research, University of Heidelberg, D-70569 Stuttgart
[2] Department of Macromolecular Science, Fudan University, Chinese Ministry of Education
[3] Technical University of Munich, Department Chemie, Lehrstuhl II for Organic Chemistry, D-85747 Garching
来源
Nano Lett. | 2007年 / 5卷 / 1413-1418期
关键词
Block copolymers - Glass - Hydrogels - Micelles;
D O I
10.1021/nl070098g
中图分类号
学科分类号
摘要
We present herein an innovative technique for decorating soft polymer surfaces with metallic nanostructures fabricated by diblock copolymer micelle nanolithography. Thus far, such nanolithography has been limited to plasma-resistant inorganic substrates such as glass. Our new development is based on the transfer of nanopatterns from glass to soft substrates. Special emphasis is given to hydrogel surfaces with respect to their properties for tailoring cell adhesion. Besides planar surfaces, periodic gold nanopatterns on curved surfaces have been fabricated, as demonstrated on the interior surface of a tubelike hydrogel, which potentially mimic situations of vessels in vivo. © 2007 American Chemical Society.
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页码:1413 / 1418
页数:5
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