Oxidative stress and changes in locomotor behavior and gill morphology of Gambusia affinis exposed to chromium

被引：46
作者：
Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad 500-007, India [1 ]
机构：
[1] Toxicology Unit, Biology Division, Indian Institute of Chemical Technology
来源：
Toxicol. Environ. Chem. | 2006年 / 2卷 / 355-365期
关键词：
Antioxidant enzymes and TBARS; Behavior; Chromium; Gills; Morphology; Sublethal; Toxicity; Viscera;
D O I：
10.1080/02772240600635985
中图分类号：
学科分类号：
摘要：
Sublethal effects of chromium trioxide on mosquito fish, Gambusia affinis , were carried out for 28 days on day 4, 8, 12, 16, 20, 24, and 28. The sublethal effects of chromium (LC 10 , 77.62 mg L-1) on antioxidant enzymes, thiobarbituric acid reactive substance (TBARS), locomotor behavior, and gill morphology were studied. The antioxidant enzymes like superoxide dismutase (SOD) and catalase were induced throughout the exposure span of 28 days. Percent induction was also increase with the days of exposure. Lipid peroxidation product, malondialdehyde was enhanced in the viscera tissue of chromium-exposed fish. Perturbation of locomotor behavior like decrease in distance travelled (m min-1) and in swimming speed (cm s-1) was observed in exposed fish. Chromium toxicity caused alterations in gill morphology like hypertrophy and hyperplasia in secondary lamellae followed by detached epithelium with severe necrosis. It can be concluded from the results that Cr intoxication in Gambusia fish, caused induction in antioxidant enzymes and lipid peroxidation, plus changes in gill morphology and locomotor behavior. © 2006 Taylor & Francis.
引用
收藏
页码：355 / 365
页数：10
相关论文
共 47 条
  • [1] Eisler R., Chromium hazards to fish, wildlife, and invertebrates: A synoptic review, Biological Report No. 85, (1986)
  • [2] Brooks K.M., Literature Review and Assessment of the Environment Risks Associated with the Use of CCA Treated Wood Products in Aquatic Environment, (1997)
  • [3] Pratap H.B., Fu H., Lock R.A.C., Wendelaar Bonga S.E., Effect of water borne and dietary cadmium on plasma ions of the teleost Oreochromis mossambicus in relation to water calcium levels, Arch. Environ. Contam. Toxicol., 18, pp. 568-575, (1989)
  • [4] Knoll J., Fromm P.O., Accumulation and elimination of hexavalent chromium in rainbow trout, Physiol. Zool., 33, pp. 1-8, (1960)
  • [5] Ghafghazi T., Maghbareh A., Barnett R., Effect of chromium on glucose tolerance in rat, Toxicol., 12, pp. 47-52, (1979)
  • [6] Browning E., Toxicity of Industrial Metals. 2nd Ed., (1969)
  • [7] Tandon S.K., Saxena D.K., Gaur J.S., Chandra S.V., Comparative study of trivalent and hexavalent chromium. Alterations in blood and liver, Environ. Res., 15, pp. 90-99, (1978)
  • [8] Behari J., Chandra S.V., Tandon S.K., Comparative toxicity of trivalent and hexavalent chromium to rabbits. III. Biochemical and histological changes in testicular tissue, Acta Biol. Med. Germ., 37, pp. 463-468, (1978)
  • [9] Bagchi D., Stohs S.J., Downs B.W., Bagchi M., Preuss H.G., Cytotoxicity and oxidative mechanisms of different forms of chromium, Toxicol., 180, 1, pp. 5-22, (2002)
  • [10] Filho Wilhelm D., Torres M.A., Tribess T.B., Pedrosa R.C., Soares C.H.L., Influence of season and pollution on the antioxidant defenses of the cichlid fish acará (Geophagus brasiliensis), Braz. J. Med. Biol. Res., 34, 6, pp. 719-726, (2001)
12345