A novel approach for direct observation of biodistribution of water-soluble carbon nanotubes in mice

被引：0

作者：

Abe, Shigeaki ^{[1
]}

Hyono, Atsushi ^{[2
]}

Watari, Fumio ^{[1
]}

Hayashi, Daisuke ^{[3
]}

Takada, Tomoya ^{[3
]}

机构：

[1] Department of Biomedical Materials and Engineering, Graduate School of Dental Medicine, Hokkaido University, Sapporo,060-8586, Japan

[2] Department of Material Science and Engineering, Faculty of Engineering, Hokkaido University, Sapporo, Japan

[3] Department of Material Chemistry, Asahikawa National College of Technology, Asahikawa, Japan

来源：

Nano Biomedicine | 2012年 / 4卷 / 02期

关键词：

Biodistributions - Direct observations - Post injection - Raman mapping - Tail veins - Transmission electron - Water-soluble carbon nanotubes;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

In this study, we investigated the biodistribution of water-soluble carbon nanotubes (CNTs) after administration through the tail vein of mice. The biodistribution was investigated using an optical and transmission electron measurement. Some of the CNTs remained in the liver and lung even 4 weeks post-injection. We also succeeded in direct observation of CNTs in the excited organs using Raman spectroscopy. In future, this method can allow to observation as a Raman mapping images of CNTs in body.

引用

页码：143 / 148