Malonyl-4,5-dihydroniphimycin: A new polyol macrolide antibiotic, produced by Streptomyces hygroscopicus

被引：0

作者：

Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., 26, 1113 Sofia, Bulgaria ^{[1
]}

机构：

[1] Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Acad. G. Bonchev Str.

来源：

Z. Naturforsch. Sect. B J. Chem. Sci. | 2007年 / 9卷 / 1187-1192期

关键词：

Antifungal and antibacterial activity; Malonyl-4,5-dihydroniphimycin; Streptomyces hygroscopicus 15;

D O I：

10.1515/znb-2007-0913

中图分类号：

学科分类号：

摘要：

Malonyl-4,5-dihydroniphimycin was isolated as a new antibiotic from the mycelium of Streptomyces hygroscopicus 15. The chemical constitution was elucidated from the physico-chemical properties, using NMR techniques and mass spectrometry, to be a 36-membered macrolide related to non-polyenic antibiotics. Malonyl-4,5-dihydroniphimycin displays activity against filamentous fungi and Gram-positive bacteria. © 2007 Verlag der Zeitschrift für Naturforschung.

引用

页码：1187 / 1192

页数：5

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