Mechanics of the stomach: A review of an emerging field of biomechanics

被引：59
作者：
Brandstaeter S. [1 ]
Fuchs S.L. [1 ,2 ]
Aydin R.C. [3 ]
Cyron C.J. [2 ,3 ]
机构：
[1] Institute for Computational Mechanics, Technical University of Munich, Garching
[2] Institute of Continuum and Materials Mechanics, Hamburg University of Technology, Hamburg
[3] Institute of Materials Research, Materials Mechanics, Helmholtz-Zentrum Geesthacht, Geesthacht
来源：
GAMM Mitteilungen | 2019年 / 42卷 / 03期
关键词：
digesta; gastric electrophysiology; gastric mechanics; gastric wall; multiphysics model;
D O I：
10.1002/gamm.201900001
中图分类号：
学科分类号：
摘要：
Mathematical and computational modeling of the stomach is an emerging field of biomechanics where several complex phenomena, such as gastric electrophysiology, fluid mechanics of the digesta, and solid mechanics of the gastric wall, need to be addressed. Developing a comprehensive multiphysics model of the stomach that allows studying the interactions between these phenomena remains one of the greatest challenges in biomechanics. A coupled multiphysics model of the human stomach would enable detailed in-silico studies of the digestion of food in the stomach in health and disease. Moreover, it has the potential to open up unprecedented opportunities in numerous fields such as computer-aided medicine and food design. This review article summarizes our current understanding of the mechanics of the human stomach and delineates the challenges in mathematical and computational modeling which remain to be addressed in this emerging area. © 2019 The Authors. GAMM - Mitteilungen published by Wiley-VCH Verlag GmbH & Co. KGaA on behalf of Gesellschaft für Angewandte Mathematik und Mechanik
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共 239 条
[1]  
Finkelstein E.A., Trogdon J.G., Cohen J.W., Dietz W., Health Aff., 28, 5, (2009)
[2]  
Camilleri M., Dubois D., Coulie B., Jones M., Kahrilas P.J., Rentz A.M., Sonnenberg A., Stanghellini V., Stewart W.F., Tack J., Talley N.J., Whitehead W., Revicki D.A., Clin. Gastroenterol. Hepatol., 3, 6, (2005)
[3]  
Overweight and Obesity among Adults, (2012)
[4]  
Wood J.D., Physiol. Gastrointest. Tract, (2018)
[5]  
Borisenko O., Colpan Z., Dillemans B., Funch-Jensen P., Hedenbro J., Ahmed A.R., Obes. Surg., 25, 8, (2015)
[6]  
Hennig G.W., Spencer N.J., Physiol. Gastrointest. Tract, (2018)
[7]  
Cremieux P.Y., Buchwald H., Shikora S.A., Ghosh A., Yang H.E., Buessing M., Am. J. Manag. Care, 14, 9, (2008)
[8]  
Gawron A.J., French D.D., Pandolfino J.E., Howden C.W., PharmacoEconomics, 32, 8, (2014)
[9]  
Oustamanolakis P., Tack J., J. Clin. Gastroenterol., 46, 3, (2012)
[10]  
Ryan K.K., Tremaroli V., Clemmensen C., Kovatcheva-Datchary P., Myronovych A., Karns R., Wilson-Perez H.E., Sandoval D.A., Kohli R., Backhed F., Seeley R.J., Nature, 509, 7499, (2014)
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