Nickel-catalyzed reductive carbonylative coupling of vinyl triflates with alkyl bromides toward enones with oxalyl chloride as the carbonyl source

被引：3

作者：

Huo, Yong-Wang ^{[1
,2
]}

Bao, Zhi-Peng ^{[1
,2
]}

Wang, Le-Cheng ^{[1
,2
]}

Schmoll, Alban ^{[1
]}

Wu, Xiao-Feng ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian Natl Lab Clean Energy, Dalian 116023, Liaoning, Peoples R China

[2] Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany

来源：

JOURNAL OF CATALYSIS | 2025年 / 442卷

关键词：

Carbonylation; Nickel; Reductive coupling; Enone; Alkyl bromide; Oxalyl chloride; DIELS-ALDER REACTION; ALPHA; BETA-UNSATURATED KETONES; HECK REACTION; CO SOURCE; HALIDES; DEHYDROGENATION; HYDROGENATION; ALDEHYDES; REAGENTS;

D O I：

10.1016/j.jcat.2024.115890

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Herein, we report a nickel-catalyzed reductive carbonylation reaction of vinyl triflates and alkyl bromides for the preparation of enones. With oxalyl chloride as a safe and readily available carbonyl source, various alkyl alkenyl ketones were prepared in moderate to good yields under relatively mild conditions. Control experiments demonstrated that the combined action of DMF and zinc facilitated the release of CO from oxalyl chloride.

引用

页数：5

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