Palladium-catalyzed cascade cyclization of α,β-unsaturated N-tosylhydrazones with iodoarenes: access to 2H-chromenes and 2H-quinolines

被引：0

作者：

Zheng, Yiyi ^{[1
]}

Zhu, Xi-Wei ^{[1
]}

Pan, Yi-Yun ^{[1
]}

Sun, Fei ^{[1
]}

Yao, Long ^{[2
]}

Wu, Xin-Xing ^{[1
]}

机构：

[1] Nantong Univ, Coll Chem & Chem Engn, Nantong 226019, Peoples R China

[2] Nantong Univ, Anal & Testing Ctr, Nantong 226019, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2024年 / 22卷 / 46期

基金：

中国国家自然科学基金;

关键词：

CROSS-COUPLING REACTIONS; ALPHA-DIAZOCARBONYL COMPOUNDS; METAL CARBENE; ENANTIOSELECTIVE SYNTHESIS; VINYL HALIDES; INSERTION; EFFICIENT; REAGENTS; SULFONYLHYDRAZONES; AMINATION;

D O I：

10.1039/d4ob01300j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A palladium-catalyzed cascade reaction of alpha,beta-unsaturated N-tosylhydrazones with iodoarene derivatives containing a nucleophilic group has been developed, which provides facile access to 2H-chromenes and 2H-quinolines, respectively. Additionally, the double Pd-carbene migratory insertion/nucleophilic substitution processes for the synthesis of a ternary heterocyclic skeleton were possible in the developed catalytic system.

引用

页码：9121 / 9124

页数：4

共 59 条

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