Synthesis, spectral characterization and antibacterial studies of palladium(II) complexes of heterocyclic thiones

被引：0
作者：
Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan [1 ]
不详 [2 ]
不详 [3 ]
机构：
[1] Department of Chemistry, Quaid-i-Azam University, Islamabad
[2] Microbiology Research Laboratory, Department of Biological Sciences, Quaid-i-Azam University, Islamabad
[3] Department of Chemistry, University of Engineering and Technology
来源：
Spectroscopy | 2009年 / 5-6卷 / 299-306期
关键词：
Antibacterial activity; NMR spectroscopy; Palladium(II); Thiones;
D O I：
10.3233/SPE-2009-0387
中图分类号：
学科分类号：
摘要：
Reactions of K2[PdCl4] with heterocyclic thiones in molar ratios of 1:2 and 1:4 in water-methanol medium yielded the palladium(II) complexes with the general formula of either [Pd(L)Cl2], [Pd(L) 2]Cl2 or [Pd(L)4]Cl2 where L = Imidazolidine-2-thione (Imt), 2-Mercaptopyridine (Mpy), 2-Mercaptopyrimidine (Mpm), 6-Mercaptopurine (6-Mp) and Thionicotinamide (Tna). The complexes were characterized by elemental analysis and spectroscopic (IR, 1H and 13C NMR) methods. An upfield shift in the >C=S resonance of thiones in 13C NMR and downfield shift in N-H or aromatic proton resonances in 1H NMR are consistent with the sulfur coordination to palladium(II). The complexes were screened for antibacterial activity, and the results showed that the complexes exhibited moderate activities as compared to that of a standard drug. © 2009 - IOS Press and the authors. All rights reserved.
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页码：299 / 306
页数：7
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