Thermo-responsive gels: Biodegradable hydrogels from enantiomeric copolymers of poly(lactide) and poly(ethylene glycol)

被引:0
|
作者
Fujiwara, Tomoko [1 ]
机构
[1] Department of Chemistry, University of Memphis, 213 Smith Chemistry Bldg., Memphis, TN 38152, United States
来源
ACS Symposium Series | 2012年 / 1114卷
关键词
Biodegradable hydrogels - Bioresorbable polymers - Injectable biomaterials - Polymer designs - Stereocomplexation - Structures and properties - Temperature changes - Thermo-responsive;
D O I
10.1021/bk-2012-1114.ch017
中图分类号
学科分类号
摘要
Hydrogels responding to temperature changes are used for injectable biomaterials with many potential applications. Specifically, biocompatible hydrogels that can be safely injected without surgery and sustained/ disintegrated in a controlled manner are of interest. Poly(lactide), PLA, is the most studied and utilized bioresorbable polymer, and its block copolymers provide a great variety of structures and properties. Hydrogels utilizing stereocomplexation of the enantiomeric PLAs offer new polymer design and properties and expand their applications. © 2012 American Chemical Society.
引用
收藏
页码:287 / 311
相关论文
共 50 条
  • [11] Double thermo-responsive hydrogels from poly(vinylcaprolactam) containing diblock and triblock copolymers
    Thomassin, Jean-Michel
    Mathieu, Kevin
    Kermagoret, Anthony
    Fustin, Charles-Andre
    Jerome, Christine
    Debuigne, Antoine
    POLYMER CHEMISTRY, 2015, 6 (10) : 1856 - 1864
  • [12] Synthesis and characterization of poly (ethylene glycol)-based thermo-responsive polyurethane hydrogels for controlled drug release
    Paris, Rodrigo
    Marcos-Fernandez, Angel
    Quijada-Garrido, Isabel
    POLYMERS FOR ADVANCED TECHNOLOGIES, 2013, 24 (12) : 1062 - 1067
  • [13] Novel synthesis of biodegradable star poly(ethylene glycol)-block-poly(lactide) copolymers
    Lemmouchi, Yahia
    Perry, Michael C.
    Amass, Allan J.
    Chakraborty, Khirud
    Schacht, Etienne
    JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2007, 45 (17) : 3966 - 3974
  • [14] pH and thermo-responsive poly(N-isopropylacrylamide) copolymer grafted to poly(ethylene glycol)
    Abdullah-Al-Nahain
    Lee, Kang Seok
    Mosaiab, Tamim
    Park, Sung Young
    JOURNAL OF APPLIED POLYMER SCIENCE, 2013, 130 (01) : 168 - 174
  • [15] Crystallization behavior of biodegradable amphiphilic poly(ethylene glycol) poly(L-lactide) block copolymers
    Kim, KS
    Chung, S
    Chin, IJ
    Kim, MN
    Yoon, JS
    JOURNAL OF APPLIED POLYMER SCIENCE, 1999, 72 (03) : 341 - 348
  • [16] Crystallization behavior of biodegradable amphiphilic poly(ethylene glycol)-poly(L-lactide) block copolymers
    Inha Univ, Inchon, Korea, Republic of
    J Appl Polym Sci, 3 (341-348):
  • [17] Inhibition of bovine serum albumin adsorption by poly(ethylene glycol) soft segment in biodegradable poly(ethylene glycol)/poly(L-lactide) copolymers
    Hu, David Shiaw-Guang, 1600, Publ by John Wiley & Sons Inc, New York, NY, United States (50):
  • [18] Novel synthesis of biodegradable poly(lactide-co-ethylene glycol) block copolymers
    Lemmouchi, Yahia
    Perry, Michael C.
    Amass, Allan J.
    Chakraorty, Khirud
    Schue, Francois
    JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2007, 45 (11) : 2235 - 2245
  • [19] INHIBITION OF BOVINE SERUM-ALBUMIN ADSORPTION BY POLY(ETHYLENE GLYCOL) SOFT SEGMENT IN BIODEGRADABLE POLY(ETHYLENE GLYCOL POLY(L-LACTIDE) COPOLYMERS
    HU, DSG
    LIU, HJ
    PAN, IL
    JOURNAL OF APPLIED POLYMER SCIENCE, 1993, 50 (08) : 1391 - 1396
  • [20] Synthesis and water-swelling of thermo-responsive poly(ester urethane)s containing poly(ε-caprolactone), poly(ethylene glycol) and poly(propylene glycol)
    Loh, Xian Jun
    Sng, Kian Boon Colin
    Li, Jun
    BIOMATERIALS, 2008, 29 (22) : 3185 - 3194