Recent advances in boron-mediated aglycon delivery (BMAD) for the efficient synthesis of 1,2-cis glycosides

被引：0

作者：

Takahashi, Daisuke ^{[1
]}

Inaba, Kazuki ^{[1
]}

Toshima, Kazunobu ^{[1
]}

机构：

[1] Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama,223-8522, Japan

来源：

Carbohydrate Research | 2022年 / 518卷

关键词：

Boron; -; Glycosides; Glycosylation; Regioselectivity; Sugars;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Highly stereoselective synthesis of 1,2-cis glycosides remains a challenging task due to the lack of reliable neighboring group participation (NGP) from the 2-O-acyl functionality in the glycosyl donor. In this context, our group recently developed highly 1,2-cis-stereoselective glycosylation methods, named boron-mediated aglycon delivery (BMAD), using organoboron reagents and 1,2-anhydroglycosyl donors. In this mini-review article, we introduce the BMAD methods and their applications to the synthesis of biologically active natural products and complex glycosides reported since our mini-review article published in this journal in 2017. © 2022 Elsevier Ltd

引用