Biopolymeric matrices based on chitosan for medical applications

被引：0
|
作者：
Mucha M. [1 ]
Balcerzak J. [1 ]
Michalak I. [1 ]
Tylman M. [1 ]
机构：
[1] Faculty of Process and Environmental Engineering, Technical University of Lodz ul, 90-924 Lodz
来源：
E-Polymers | 2011年
关键词：
D O I：
10.1515/epoly.2011.11.1.21
中图分类号：
学科分类号：
摘要：
Chitosan (CS) based materials in a form of composite with poly(lactic acid) (PLA) granules, films and freeze-dried scaffolds also with blend form with hydroxypropylocellulose (HPC), as well as dibutyrylchitin films were obtained. These structures are intended especially for controlled drug delivery systems, including transdermal and oral dosage forms. Excellent adhesion of biopolymer matrices to PLA microspheres or hydroxyapatite (HAp) particles was proven. The Iorder drug (ibuprofen (IBU)) release kinetics from obtained films is stated.
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