A fluorescence turn-on strategy to achieve detection of captopril based on Ag nanoclusters

被引:0
|
作者
Xi L. [1 ]
Zhang X. [1 ]
Chen Y. [1 ]
Peng J. [4 ]
Liu M. [1 ]
Huo D. [1 ]
Li G. [5 ]
He H. [1 ,2 ,3 ]
机构
[1] Department of Chemistry, China Pharmaceutical University, Nanjing
[2] Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing
[3] Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing
[4] College of Medical Engineering & the Key Laboratory for Medical Functional Nanomaterials, Jining Medical University, Jining
[5] College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing
来源
Chemical Physics Letters | 2022年 / 807卷
关键词
Ag nanoclusters; Captopril; Detection; Fluorescence;
D O I
10.1016/j.cplett.2022.140085
中图分类号
学科分类号
摘要
In this work, a fluorescence method based on a turn-on strategy to achieve detection of captopril was established utilizing Ag nanoclusters(AgNCs). Captopril as the second ligand can protect AgNCs through the Ag-S bond, promoting electron transfer on the surface of nanoclusters and enhancing the fluorescence intensity of AgNCs. Therefore, a sensitive method to detect captopril was achieved, which shown a good linear range from 5 to 60 μM with low limit of detection (1.12 μM). The proposed fluorescence detection system was applied in practical serum samples, indicating satisfying recovery and providing a simple and sensitive strategy for detection of captopril. © 2022 Elsevier B.V.
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