Photoinduced Metal-Free Decarboxylative Fluoroalkylation of Alkenes for the Synthesis of N-Arylbutanamides and Oxindoles

被引：2

作者：

Ji, Yi-Gang ^{[1
]}

Li, Zhuo-Hong ^{[1
]}

Yang, Yu-Qing ^{[1
]}

Yang, Xiaohu ^{[3
]}

Yang, Wen-Chao ^{[2
]}

机构：

[1] Jiangsu Second Normal Univ, Coll Life Sci & Chem, Jiangsu Key Lab Biofunct Mol, Nanjing 210013, Peoples R China

[2] Yangzhou Univ, Sch Plant Protect, Yangzhou 225009, Peoples R China

[3] Zhejiang Hosp, Dept Pharm, Hangzhou 310013, Zhejiang, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2024年 / 30卷 / 68期

关键词：

decarboxylation; fluoroalkylation; photochemical; metal-free; C-H TRIFLUOROMETHYLATION; OXIDATIVE DECARBOXYLATION; ACID-DERIVATIVES; CARBOXYLIC-ACIDS; ACCESS; ARENES; DIFLUOROACETATES; CATALYST;

D O I：

10.1002/chem.202402891

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The visible light-induced decarboxylative cascade reaction of fluoroalkyl carboxylic acids has been achieved for the efficient synthesis of fluorinated compounds. However, most of the transformations rely on noble iridium metal complex. Herein, a visible light-induced metal-free decarboxylative cascade reaction of fluoroalkyl carboxylic acids has been realized. This protocol features simple operation, transition metal free, and good functional group tolerance.

引用

页数：4

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